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Tanda Lugovskaya

Интересная статья по тому, как травма эпигенетически передаётся следующим поколениям.

Статья не то чтобы о совсем неизвестном - понятия "эпигеном" и "метилирование ДНК" не вчера появились - но показывает наглядно:

"Yehuda uncovered an epigenetic mark in Holocaust survivors and their offspring, a group at greater risk for mental health challenges. She assessed 32 survivors and their adult children in 2015, examining the FKBP5 gene—which has been linked to anxiety and other mental health concerns.
By extracting DNA from blood samples, the team identified epigenetic changes in the same region of the gene in the survivors and their children; but those alterations were not present in the DNA of a small group of Jewish parents and their offspring who lived outside of Europe and didn’t experience the Holocaust.
Yehuda found that there were lower levels of DNA methylation in the FKBP5 gene in children whose mothers survived the Holocaust than in Jewish control subjects whose parents didn’t experience the Holocaust. Some studies have linked reduced DNA methylation in the FKBP5 gene to increased risk of disorders in adults such as PTSD. The results suggested that a mother’s trauma—even if it occurred during childhood—might lead to epigenetic changes within the DNA in her eggs and thus impact the mental health of her children."

Минимум 80 лет оно держится...

Аналогично:

"A 2019 study with male Vietnam war veterans from Australia provides additional clues about how trauma transcends generations.
Researchers searched for methylation differences in the DNA encapsulated in the sperm of veterans suffering from PTSD and compared it to DNA of those without the condition. Ten regions of DNA showed different methylation patterns in PTSD veterans compared to non-PTSD veterans. The changes were present in nine different associated with psychiatric disorders such as PTSD.
The methylation patterns in the vets with PTSD were linked with mental health conditions diagnosed in the veterans' children, according to the study. The findings identified a unique pattern of DNA changes which could be inherited, “especially those that are associated with the stress response,” says Divya Mehta, senior research fellow at Queensland University of Technology in Australia."

Не то чтобы в этом смысле люди были уникальны. Вообще-то нет:

"Still, the study found that the pups and their descendants exhibited depression, memory deficits, and risk-taking behaviors, such as an inability to evaluate potential dangers, among many behavioral changes. While the depression and memory decline extended to the third generation, the risk-taking started to diminish only after the fifth generation."

Что обнадёживает - это можно править. Обогащённая среда (где - интересно), ряд препаратов и физнагрузка - наши друзья по части улучшения ситуации.

Но - бережём себя, драги други. Мы довольно хрупкие. Правда, и устойчивые тоже, тем и выжили, конечно.

https://www.nationalgeographic.com/premium/article/trauma-genes-inherit-epigenetics-methylation

Can trauma be inherited through genes?
A life-altering experience “doesn’t just die with you,” one expert says. “It has a life of its own afterwards.”
PremiumWWW.NATIONALGEOGRAPHIC.COM
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